Irf3 compound name
WebWe have detected that you are are on a small device such as a mobile phone. We recommend you use a larger device to draw your structure. Still want to try? Try rotating the device so that it is in a landscape position. IRF3 is a member of the interferon regulatory transcription factor (IRF) family. IRF3 was originally discovered as a homolog of IRF1 and IRF2. IRF3 has been further characterized and shown to contain several functional domains including a nuclear export signal, a DNA-binding domain, a C-terminal IRF association … See more Interferon regulatory factor 3, also known as IRF3, is an interferon regulatory factor. See more IRF3 has been shown to interact with IRF7. See more • Pitha PM, Au WC, Lowther W, Juang YT, Schafer SL, Burysek L, Hiscott J, Moore PA (1999). "Role of the interferon regulatory factors (IRFs) in virus-mediated signaling and regulation of cell growth" See more • Interferon+Regulatory+Factor-3 at the U.S. National Library of Medicine Medical Subject Headings (MeSH) • FactorBook IRF3 See more
Irf3 compound name
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WebBerkeleyacetal C. Berkeleyacetal C, a meroterpenoid compound, shows favorable activity of inhibiting nitrogen oxide (NO) production of macrophages stimulated by … WebWe sought to develop a small-molecule activator of interferon regulatory factor 3 (IRF3), an essential innate immune transcription factor, which could potentially be used therapeutically in multiple disease settings. Using a high-throughput screen, we identified small-molecule entities that activate a type I interferon response, with minimal off-target NFκB activation. …
WebIridium (III) Fluoride molecular weight Molar mass of IrF3 = 249.2122096 g/mol Convert grams Iridium (III) Fluoride to moles or moles Iridium (III) Fluoride to grams Molecular … WebJul 25, 2024 · We first demonstrated that IRF3 and IRF7 underwent liquid–liquid phase separation (LLPS), a general regulatory mechanism that enables the creation of …
WebNov 13, 2024 · Therefore, our study identifies IRF3 as a negative regulator of the Wnt/β-catenin pathway and a potential prognosis marker for Wnt-related tumorigenesis, and describes an intriguing link between gut microbiota and CRC via the IRF3-β-catenin axis. Subject terms: Gynaecological cancer, Cell biology, Gastroenterology Introduction WebMay 7, 2024 · Property Name Property Value Reference; Molecular Weight: 409.08: Computed by PubChem 2.1 (PubChem release 2024.05.07) XLogP3-AA: 3.9: Computed by XLogP3 3.0 (PubChem release 2024.05.07) Hydrogen Bond Donor Count: 1: Computed by Cactvs 3.4.8.18 (PubChem release 2024.05.07) Hydrogen Bond Acceptor Count: 4: …
WebMar 21, 2024 · IRF3 provided by HGNC Official Full Name interferon regulatory factor 3 provided by HGNC Primary source HGNC:HGNC:6118 AllianceGenome:HGNC:6118 Gene …
WebJun 1, 2024 · One of the major PRRs leading to IRF3 activation is toll-like receptor 3 (TLR3), which is a critical receptor for viral double stranded RNA. The binding of TLR3 to its ligand … incompleteread: incompletereadWebNov 13, 2024 · IRF3 in intestinal epithelium protects against colonic tumorigenesis IRF3 −/− mice or wild-type littermates were administrated with azoxymethane (AOM) and dextran sulfate sodium (DSS).... incompletely united fractureWebMar 9, 2024 · DNA-PK is a DNA sensor for IRF-3-dependent innate immunity. These data show that IRF3 plays a crucial role in development of Th17 responses and EAE and warrants investigation in human multiple sclerosis. identified IRF3 as a novel regulator of peroxisome proliferator-activated receptor gamma. incompleteness procedurehttp://www.endmemo.com/chem/chemsearch.php incompletion procedureWebIdentification and Characterization of Small-Molecule IRF3-Dependent Immune Activators for Pharmaceutical Development . Authors Marie H Foss 1 , Susan L Stevens 1 , Haihong … incompleteness of fossil recordWebJun 1, 2024 · The interferon regulatory factor (IRF) family of transcription factors play a vital role in the human innate antiviral immune responses with production of (IFNs) as a hallmark outcome of activation. In recent years, IRF3 Graphical abstract Keywords IKKε NAP1 TBKBP1 TANK Abbreviations IRF Interferon regulatory factor IFNs Interferons TI-IFNs incompliance meanWebIrf3 - interferon regulatory factor 3 Mus musculus Synonyms: C920001K05Rik, IRF-3, Interferon regulatory factor 3 , Bibeau-Poirier, A. , , Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. incompliance ohio