Ctgf growth factor

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August undefined, 2024

WebAug 6, 2024 · Connective tissue growth factor (CTGF) is a member of the CCN matricellular protein family, consisting of four domains, that regulates the signaling of other growth factors and promotes kidney fibrosis. Main body of the abstract. CTGF can simultaneously interact with several factors with its four domains. The microenvironment …

Connective Tissue Growth Factor in Idiopathic Pulmonary …

WebAug 6, 2008 · Connective tissue growth factor (CTGF=CCN2), one of six members of cysteine-rich, secreted, heparin-binding proteins with a modular structure, is recognized as an important player in fibrogenic pathways as deduced from findings in non-hepatic tissues and emerging results from liver fibrosis. Collectively, the data show strongly increased ... WebMay 28, 2024 · The overexpression of a matricellular protein, connective tissue growth factor (CTGF), is a hallmark of fibrosis in multiple tissues in the mediation of the pro … how many pounds is 350 gsm

CTGF expression. CTGF, connective tissue growth factor; CTX, …

WebTissue proteome. GENERAL INFORMATIONi. General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions … WebJul 22, 2002 · Connective-tissue growth factor (CTGF) is a secreted protein implicated in multiple cellular events including angiogenesis, skeletogenesis and wound healing 1. It is … WebHuman connective tissue growth factor (CTGF), also known as CCN2, and Insulin-like growth factor-binding protein 8, is a matricellular protein encoded by the gene CTGF. Along with CYR61 (CCN1) and NOV (CCN3), CTGF belongs to the CCN family of extracellular matrix-associated heparin binding proteins. The CCN proteins contain IGFBP, Von ... how many pounds is 340kg

Frontiers Connective Tissue Growth Factor: From

CTGF Protein Connective Tissue Growth Factor CCN2 ProSpec

WebConnective tissue growth factor (CTGF) is a secreted protein that binds to integrins, and regulates the invasiveness and metastasis of certain carcinoma cells. Here, we found that CTGF was upregulated in drug-resistant phenotype of human CRC cells. Overexpression of CTGF enhanced the resistance to 5-FU-induced cell apoptosis. WebAug 1, 2024 · CTGF (connective tissue growth factor), also known as CCN2, is one of the best-studied members of the CCN family [1], a family of regulatory proteins of the … how many pounds is 3500 kgWebFeb 16, 2024 · Connective tissue growth factor (CTGF) expression in hepatic stellate cells (HSCs) and liver endothelial cells correlates with the extent of acute liver injury, and upregulated CTGF expression was ... how many pounds is 350 kg

"CTGF, also known as CCN2 or connective tissue growth factor, is a matricellular protein of the CCN family of extracellular matrix-associated heparin-binding proteins (see also CCN intercellular signaling protein). CTGF has important roles in many biological processes, including cell adhesion, migration, … See more Members of the CCN protein family, including CTGF, are structurally characterized by having four conserved, cysteine-rich domains. These domains are, from N- to C-termini, the insulin-like growth factor … See more Knockout mice with the Ctgf gene disrupted die at birth due to respiratory stress as a result of severe chondrodysplasia. Ctgf-null mice also show defects in angiogenesis, with impaired interaction between endothelial cells and pericytes … See more • Ctgf/hcs24 CAESAR • CYR61 (CCN1) See more CTGF is associated with wound healing and virtually all fibrotic pathology. It is thought that CTGF can cooperate with TGF-β to induce sustained fibrosis and to exacerbate extracellular matrix production in association other fibrosis-inducing conditions. … See more • Human CTGF genome location and CTGF gene details page in the UCSC Genome Browser. See more " - Ctgf growth factor

Ctgf growth factor

CTGF Protein Connective Tissue Growth Factor CCN2 ProSpec

WebConnective tissue growth factor (CTGF/CCN2) ELISA: a novel tool for monitoring fibrosis -Dendooven A, Gerritsen KG, Nguyen TQ, Kok RJ, … WebConnective Tissue Growth Factor/CCN2. CTGF is a cysteine-rich 40 kDa matricellular growth factor implicated in angiogenesis, wound healing, and development. Although it …

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WebApr 1, 2024 · Based on numerous studies through the decades, the connection between CTGF and the well-known fibrosis-related growth factor transforming growth factor-β (TGF-β) was revealed.The induction of fibrosis by CTGF through different molecular pathways have been reported in the model of hepatic fibrosis, pulmonary fibrosis, renal … WebConnective tissue growth factor (CTGF, CCN2) CTGF (also called CCN2), a member of the CCN family of matricellular proteins, has long been known to promote differentiation and proliferation of chondrocytes and osteoblasts (for a review, see Takigawa et al., 2003). CCN2 promotes fibroblast proliferation, matrix production, and granulation tissue ...

WebApr 13, 2024 · The identification of tissue-specific promoters for gene therapeutic constructs is one of the aims of complex tumor therapy. The genes encoding the fibroblast activation protein (FAP) and the connective tissue growth factor (CTGF) can function in tumor-associated stromal cells but are practically inactive in normal adult cells. Accordingly, the … WebConnective tissue growth factor (CTGF) is a member of the CCN family of secreted, matrix-associated proteins encoded by immediate early genes that play various roles in …

WebConnective tissue growth factor (CTGF) is a cysteine-rich protein the synthesis and secretion of which are hypothesized to be selectively regulated by activins and other … WebAug 1, 1997 · Abstract Connective tissue growth factor (CTGF) is a novel cysteine-rich, secreted peptide, which is implicated in human atherosclerosis and fibrotic disorders …

WebMay 8, 2024 · Connective tissue growth factor (CTGF), a secreted protein, is thought to be involved in extracellular matrix remodeling during development and pathologic …

WebApr 13, 2024 · The identification of tissue-specific promoters for gene therapeutic constructs is one of the aims of complex tumor therapy. The genes encoding the fibroblast … how many pounds is 350 gramsWebConnective tissue growth factor (CTGF) is a member of the CCN (CTGF, cysteine-rich angiogenic protein 61, and nephroblastoma overexpression gene) family of regulatory … how many pounds is 3.5 kgWebApr 13, 2024 · HIGHLIGHTS who: Samuele Negro from the Eight to ten week-old , mice were employed for laser capture microdissection (LCM) and transcriptional profiling, and for electrophysiological recordingsC BL/, mice expressing cytosolic … Hydrogen peroxide induced by nerve injury promotes axon regeneration via connective tissue growth … how many pounds is 35 kgsWebFeb 16, 2024 · Connective tissue growth factor (CTGF) expression in hepatic stellate cells (HSCs) and liver endothelial cells correlates with the extent of acute liver injury, and … how many pounds is 3.5 litersWebSelect search scope, currently: articles+ all catalog, articles, website, & more in one search; catalog books, media & more in the Stanford Libraries' collections; articles+ journal articles & other e-resources how common is recurrent pericarditisWebConnective Tissue Growth Factor or CTGF is a protein of the extracellular matrix variety. Also known as CCN2, this matricellular protein is part of the CNN group. Connective … how common is radiation therapyWebAug 25, 2009 · Connective tissue growth factor (CTGF) is a secreted protein that is strongly induced in human and experimental heart failure. CTGF is said to be profibrotic; however, the precise function of CTGF is unclear. We generated transgenic mice and rats with cardiomyocyte-specific CTGF overexpression (CTGF-TG). To investigate CTGF as … how common is raynaud\u0027s disease